HotSpring, Caldera, Tiger River, Limelight and Hot Spot tubs all need a sub panel to divide the power into two circuits and provide better GFI protection. For some models that sub panel comes included with the spa, for other models it is an extra - those models are convertible to run on 110 or 220.
The finished wiring for these spas is the same plus or minus one wire - Run 50 amp four-wire to the sub, then six wires from sub to tub. Five if it's a convertible model.
So - if you pre-run 50 amp to a j-box and then 3/4" empty conduit to the area the spa will go, you should cover just about all cases - you could put a sub panel in place of the j box if you purchase a Watkins or a Sundance, or leave the j box for other brands, or even put in a generic 'spa box' if you buy a tub which needs that.
8-)